Naslov
Solid-state chemistry and polymorphism of the nucleobase adenine

Autori
Stolar, Tomislav ; Lukin, Stipe ; Požar, Josip ; Užarević, Krunoslav ; Meštrović, Ernest ; Halasz Ivan

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
The Twenty-fourth Croatian-Slovenian Crystallographic : Meeting-Book of Abstracts / Bijelić, Mirjana ; Cetina, Mario ; Čobić, Andrea ; Matković-Čalogović, Dubravka ; Popović, Stanko ; Štefanić, Zoran ; Tonejc, Antun ; Višnjevac, Aleksandar - Zagreb : Hrvatska akademija znanosti i umjetnosti (HAZU) ; Hrvatska kristalografska zajednica HAZU, 2016, 18-18

Skup
Croatian-Slovenian Crystallographic Meeting (24 ; 2016)

Mjesto i datum
Bol, Hrvatska, 21.09.2016. - 25.09.2016

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Nije recenziran

Ključne riječi
solid-state, polymorphism, adenine

Sažetak
The nucleobase adenine plays a vital role in the chemistry of life and is becoming increasingly interesting as a building block in the synthesis of functional solid materials. In this comprehensive study, it is shown that adenine is often found as a mixture of two polymorphs exhibit layered structures with different hydrogen-bonding patterns within layers. The crystal structure of the new polymorph was elucidated using synchrotron powder X-ray diffraction. Polymorph occurrence conditions, interconversion, and the difference in their thermodynamic stability were established theoretically as well as experimentally. Studies revealed that polymorph with Z' = 2 (known) is stable relative to the polymorph with Z' = 1 (new). The adenine layers in both polymorphs are connected by weak interactions likely resulting in stacking faults which are manifested in anisotropic line broadening of their powder diffraction patterns. Analysis of a few commercial samples of adenine revealed them all to be a polymorph mixture, which could be inconvenient in experiments where properties of the solid material could be relevant.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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