Naslov
Multicentric glial brain tumors of a varying degree of differentiation in patient with chronic lymphocytic leukemia : case report

Autori
Pejša, Vlatko ; Grgurević, Ivica ; Pažanin, Leo ; Lang, Nada ; Grgurević, Lorovka ; Jakšić, Ozren

Izvornik
American journal of hematology (0361-8609) 79 (2005), 1; 50-53

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
leukemia ; B-cell ; chronic ; brain neoplasms ; glioma

Sažetak
Chronic lymphocytic leukemia is associated with an increased incidence of secondary neoplasms. Primary brain tumors are rarely seen ; however, an increased risk relative to the general population has been observed in male patients with chronic lymphocytic leukemia. A case report of a 62-year-old man with progressive chronic lymphocytic leukemia and pronounced neurologic symptoms is presented. Richter’s syndrome or brain infiltration with leukemia cells was clinically suspected and suggested by computed tomography findings. Progression of the neurologic symptoms rapidly continued and the patient died. Neuropathologic examination revealed multicentric glial tumors of a varying degree of differentiation located throughout the brain and cerebellum.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA