Pregled bibliografske jedinice broj: 883380
NITRIC OXIDE: A ROLE IN LEBER’S HEREDITARY OPTIC NEUROPATHY
NITRIC OXIDE: A ROLE IN LEBER’S HEREDITARY OPTIC NEUROPATHY // Annual Meeting of the Italian Group of Biomembranes and Bioenergetics (GIBB)
Udine, Italija, 2015. (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 883380 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
NITRIC OXIDE: A ROLE IN LEBER’S HEREDITARY OPTIC NEUROPATHY
Autori
Falabella, Micol ; Forte, Elena ; Radić, Kristina ; Magnifico, Maria Chiara ; Arese, Marzia ; Giuffrè, Alessandro ; Salvetti, Marco ; Sarti, Paolo
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Skup
Annual Meeting of the Italian Group of Biomembranes and Bioenergetics (GIBB)
Mjesto i datum
Udine, Italija, 18.06.2015. - 20.06.2015
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Leber’s hereditary optic neuropathy ; nitric oxide
Sažetak
Peripheral blood mononuclear cells (PBMCs), derived from a female LHON patient with bilateral reduced vision and carrying the pathogenic mutation 11778/ND4 were observed. Viability assays with the tetrazolium dye MTT showed that lymphoblasts from the patient are more sensitive to prolonged NO exposure, leading to cell death.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
