Naslov
BMPs in Inflammation

Autori
Grgurević, Lovorka ; Dumić-Čule, Ivo ; Vukičević, Slobodan

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, stručni

Knjiga
Bone Morphogenetic Proteins: Systems Biology Regulators

Urednik/ci
Vukičević, Slobodan ; Sampath T Kuber

Izdavač
Springer

Godina
2017

Raspon stranica
357-366

ISBN
978-3-319-47505-9

Ključne riječi
Bone morphogenetic protein, Inflammatory bowel disease, Iron metabolism, Rheumatoid arthritis, Atherosclerosis

Sažetak
Bone morphogenetic proteins are regulators of embryonic development with multiple functions in adult organs and tissues. Here we summarize effects of BMPs outside the musculoskeletal system, focused on their role in inflammatory disorders, e.g., fibrosis, inflammatory bowel disease, anchylosing spondylitis, and rheumatoid arthritis. Additionally, we discuss the interplay between BMPs and vascular disorders leading to atherosclerosis and decipher the key role of BMP in iron metabolism.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA