Naslov
Primjena autolognog kondicioniranog seruma u nekirurškoj i kirurškoj parodontnoj terapiji
(Application of autologous conditioned serum in non-surgical and surgical periodontal therapy)

Autori
Puhar, Ivan ; Piskač, Marin ; Plančak, Darije

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Sažeci kongresa Hrvatski parodontološki dani 2015. Zagreb, Hrvatska, 10.-11.4.2015. U: Acta Stomatologica Croatica 2015 ; 49(2) / Puhar, Ivan - Zagreb, 2015, 186-186

Skup
Hrvatski parodontološki dani 2015.

Mjesto i datum
Zagreb, Hrvatska, 10.04.2015. - 11.04.2015

Vrsta sudjelovanja
Ostalo

Vrsta recenzije
Domaća recenzija

Ključne riječi
autologni kondicionirani serum ; parodontitis ; inicijalna terapija
(autologous conditioned serum ; periodontitis ; nonsurgical periodontal therapy)

Sažetak
Periodontal pathogens and destructive host responses are involved in the initiation and progression of periodontitis in the individual at risk for disease. Therefore, the successful long- term management of this disease may require a treatment strategy that integrates therapies that address all of these components. Autologous conditioned serum (ACS) is a biological method based on exposure of blood leukocytes to glass spheres surfaces that elicits an accumulation of anti-inflammatory cytokines, including interleukin-1 receptor antagonist, and several growth factors. The main rationale for the use of ACS is to locally deliver patient’s own anti- inflammatory cytokines into treated sites, and especially to saturate IL-1 receptors with IL-1ra as much as possible. Considering the composition of ACS and pathogenesis of periodontitis it is hypothesized that local application of ACS could contribute to better outcomes of non- surgical and surgical periodontal therapy. This presentation discusses the potential ways of ACS’s delivery in a course of periodontal therapy. Preliminary clinical results indicate that ACS could be a beneficial adjunct in the non-surgical treatment of severe generalized periodontitis. Further research in this field would also facilitate fabrication of individualized treatment for periodontal disease targeting inflammatory host response.

Izvorni jezik
Hrvatski, engleski

Znanstvena područja
Dentalna medicina

POVEZANOST RADA