Pregled bibliografske jedinice broj: 877603
Epigenetic alterations in heavy metal stressed earthworms
Epigenetic alterations in heavy metal stressed earthworms // 30th New European Society for Comparative Physiology and Biochemistry Unraveling complexity: from molecules to ecosystems
Barcelona, 2016. str. 41-41 (predavanje, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 877603 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Epigenetic alterations in heavy metal stressed earthworms
Autori
Šrut Maja, Drechsel Victoria, Nemati Niloofar, Salvatore Manuel, Höckner Martina
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
30th New European Society for Comparative Physiology and Biochemistry Unraveling complexity: from molecules to ecosystems
/ - Barcelona, 2016, 41-41
Skup
ESCPB Comparative Biochemistry and Physiology
Mjesto i datum
Barcelona, Španjolska, 04.09.2016. - 07.09.2016
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
DNA methylation, earthworms, cadmium
Sažetak
Emerging evidence suggests that soil heavy metal pollution can alter epigenetic marks in soil fauna, with DNA methylation as one of the underlying mechanisms - a process which can be persistent and even heritable. The aim of this study was to assess the consequences of chronic heavy metal exposure on genome wide DNA methylation in the earthworm Lumbricus terrestris. Earthworms were exposed to low (10 mg/kg) environmentally relevant concentration of cadmium (Cd) for a period of 3 months. Through the exposure period, the overall health status of the earthworms was monitored at the cellular (DNA damage, oxidative stress, lipid damage) and organismic level (fitness, reproductive success). Genome wide DNA methylation status was assessed by methylation sensitive amplification polymorphism (MSAP) at the beginning of the exposure and after 1 and 3 months exposure. During the exposure, earthworm fitness and cellular mechanisms remained unaffected by Cd. However, on the epigenetic level, already after 1 month of exposure, Cd induced significant increase in DNA methylation, which remained constant until the end of the exposure. The results of this study demonstrate that low levels of environmental pollution can lead to the occurrence of subtle epigenetic modifications, even when no impacts on the cellular and organismic level can be observed.
Izvorni jezik
Engleski
Znanstvena područja
Biologija
