Pregled bibliografske jedinice broj: 876371
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging // ADMET & DMPK, 2 (2014), 3; 185-190 doi:10.5599/admet.2.3.123 (recenziran, članak, znanstveni)
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Naslov
Electrochemistry of Redox-active Mn Porphyrin- based SOD Mimic MnTnBuOE-2-PyP5+ - Study of Redox Species Involved in ROS/RNS Scavenging
Autori
Weitner, Tin ; Batinić-Haberle, Ines
Izvornik
ADMET & DMPK (1848-7718) 2
(2014), 3;
185-190
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
metalloporphyrins ; oxidative stress ; superoxide ; peroxynitrite ; cyclic voltammetry
Sažetak
Manganese ortho tetrakis(N-n- butoxyethylpyridinium-2-yl)porphyrin, MnTnBuOE- 2-PyP5+, is a third-generation redox-active compound currently undergoing preclinical exploration. This work is intended to complement the already extensive research of its chemical and biological properties by a simple electrochemical study. The thermodynamic parameters related to the Mn(IV) porphyrin species of MnTnBuOE-2-PyP5+ determined in this work support its observed reactivity as an efficient scavenger of peroxynitrite. The corresponding driving forces for the possible single-electron or two-electron reductions of ONOO- have been estimated as well.
Izvorni jezik
Engleski
Znanstvena područja
Kemija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- CA Search (Chemical Abstracts)
