Naslov
Fullerol C60(OH)24 nanoparticles and mycotoxigenic fungi: A preliminary investigation into modulation of mycotoxin production

Autori
Kovač, Tihomir ; Šarkanj, Bojan ; Klapec, Tomislav ; Borišev, Ivana ; Kovač, Marija ; Nevistić, Ante ; Strelec, Ivica

Izvornik
Environmental science and pollution research (0944-1344) 24 (2017), 20; 16673-16681

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Fullerol C60(OH)24 ; nanoparticles ; Aspergillus flavus ; mycelial growth ; aflatoxin production ; oxidative stress

Sažetak
Increased use of fullerols in various fields and expected increase of their environmental spread impose the necessity for testing fullerol nanoparticles (FNP) effects on microbiota. There is little information available on the interaction of mycotoxigenic fungi and FNP, despite FNP having a great potential of modifying mycotoxin production. Namely, FNP exhibit both ROS-quenching and ROS- producing properties, while oxidative stress stimulates mycotoxin synthesis in the fungi. In order to shed some light on the extent of interaction between FNP and mycotoxigenic fungi, the effects of fullerol C60(OH)24 nanoparticles (10, 100, 1000 ng/ml) on mycelial growth, aflatoxin production and oxidative stress modulation in an aflatoxigenic strain of Aspergillus flavus (NRRL 3251) during 168 hr of incubation in a liquid culture medium were examined. FNP slightly reduced mycelial biomass weight, but significantly decreased aflatoxin concentration in media. Lipid peroxide content, superoxide dismutase, catalase and glutathione peroxidase activities suggest that FNP treatments hormetically reduced oxidative stress within fungal cells in turn suppressing aflatoxin production. These findings contribute to the assessment of environmental risk and application potential of fullerols.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija, Prehrambena tehnologija

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