Pregled bibliografske jedinice broj: 866045
Generating and measuring photochemical changes inside the brain using optical fibers: exploring stroke
Generating and measuring photochemical changes inside the brain using optical fibers: exploring stroke // Biomedical Optics Express, 5 (2014), 11; 3975-3980 doi:10.1364/BOE.5.003975 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 866045 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Generating and measuring photochemical changes inside the brain using optical fibers: exploring stroke
Autori
Tsiminis, Georgios ; Klarić, Thomas Stephen ; Schartner, Erik ; Warren-Smith, Stephen ; Lewis, Martin David ; Koblar, Simon Andrea ; Monro, Tanya
Izvornik
Biomedical Optics Express (2156-7085) 5
(2014), 11;
3975-3980
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Fiber optics sensors ; Medical optics and biotechnology ; Medical optics instrumentation ; Spectroscopy ; Fluorescence and luminescence
Sažetak
We report here on the development of a method for inducing a stroke in a specific location within a mouse brain through the use of an optical fiber. By capturing the emitted fluorescence signal generated using the same fiber it is possible to monitor photochemical changes within the brain in real-time, and directly measure the concentration of the stroke-inducing dye, Rose Bengal, at the infarct site. This technique reduces the requirement for post-operative histology to determine if a stroke has successfully been induced within the animal, and therefore opens up the opportunity to explore the recovery of the brain after the stroke event.
Izvorni jezik
Engleski
Znanstvena područja
Fizika, Biologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
