Naslov
Evidence on Major Gene Control of Cortical Index in Pedigree Data from Middle Dalmatia, Croatia

Autori
Škarić-Jurić, Tatjana

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni

Skup
Anthropology and Health: Genetics of Complex Diseases

Mjesto i datum
Hvar, Hrvatska, 09.06.2001. - 15.06.2001

Vrsta sudjelovanja
Predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
osteoporosis; complex segregation analysis; cortial index; ageing

Sažetak
The results of complex segregation analysis of cortical index pedigree data from Middle Dalmatian islands' population were presented and discussed in wider context of issues connected with genetic investigations of complex diseases. Specifically the question if the results of complex segregation analysis could serve as plausible identifier of target phenotype and target population for further molecular-genetic analyses. Definition of osteoporosis as well as it&#8217 ; s epidemiological data shows how genetic investigations of complex diseases are faced with questions starting from defining the borders between disease and "normal" ageing to the problems connected with choice of best phenotype and best target population. The results of current genetic - linkage and association - studies using diverse phenotypes in order to investigate genetics of osteoporosis were discussed.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Javno zdravstvo i zdravstvena zaštita, Etnologija i antropologija

POVEZANOST RADA