Naslov
The impact of sleep deprivation on brain

Autori
Trošt Bobić, Tatjana ; Šečić, Ana ; Zavoreo, Iris ; Matijević, Valentina ; Filipović, Branimir ; Kolak, Željka ; Bašić Kes, Vanja ; Ciliga, Dubravka ; Sajković, Dubravka

Izvornik
Acta clinica Croatica (0353-9466) 55 (2016), 3; 496-473

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
sleep deprivation ; cognition ; brain

Sažetak
Each sleep phase is characterized by specific chemical, cellular and anatomic events of vital importance for normal neural functioning. Different forms of sleep deprivation may lead to a decline of cognitive functions in individuals. Studies in this field make a distinction between total sleep deprivation, chronic sleep restriction, and the situation of sleep disruption. Investigations covering the acute effects of sleep deprivation on the brain show that the discovered behavioral deficits in most cases regenerate after two nights of complete sleep. However, some studies done on mice emphasize the possible chronic effects of long-term sleep deprivation or chronic restriction on the occurrence of neurodegenerative diseases such as Alzheimer’s disease and dementia. In order to better understand the acute and chronic effects of sleep loss, the mechanisms of neural adaptation in the situations of insufficient sleep need to be further investigated. Future integrative research on the impact of sleep deprivation on neural functioning measured through the macro level of cognitive functions and the micro molecular and cell level could contribute to more accurate conclusions about the basic cellular mechanisms responsible for the detected behavioral deficits occurring due to sleep deprivation.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kineziologija

POVEZANOST RADA