Naslov
Effect of fermanted milk on induction of modilation

Autori
Franekić, Jasna ; Nekić, K. ; Bačun-Družina, Višnja ; Pehadžić, Jasminka

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts/Mutation Res 360 / - : Elsevier, 1996

Skup
25th Annual Meeting of European Environmental Society

Mjesto i datum
Noordwijkerhout, Nizozemska, 18.06.1996. - 23.06.1996

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Salmonella typhimurium; mutagenic ativity; sodium azide

Sažetak
The human diet which is complex mixture of chemical entities, containsa anticarcinogens. Dietary intake of natural antioxidans may be yoghurt against known mutagens sodium azide (NaNO_3) and 4-nitroquinaline N-oxide (4NQO) were investigated using 4 strains of salmonella typhimurium (TA100, TA1535, TA98, TA1538). The mutagen solution was incubated for 1h at 37^Cwith yoghurt before performing the Ames test. Concurrent negative(S.typhimurium alone or S.typhimurium with yoghurt) and positive (S.typhimurium with mutagen but withought yoghurt) controls were also performed. The mutagenic activity of 4NOO in all strains and NaNO_3 instrains TA100 and TA1535 was reduced. With our present knowledge itis pnly possible to speculate on the mechanisms of antimutagenic activity of fermanted milk. Possible both direct inactivation and inhibition of enzymatic activity of the mutagen could be involved.

Izvorni jezik
Engleski

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