Pregled bibliografske jedinice broj: 854404
Wnt signaling is activated in human astrocytomas
Wnt signaling is activated in human astrocytomas // Wnt Meeting 2016 EMBO Conference
Brno, Češka Republika, 2016. (poster, međunarodna recenzija, sažetak, znanstveni)
CROSBI ID: 854404 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Wnt signaling is activated in human astrocytomas
Autori
Pećina-Šlaus, Nives ; Kafka, Anja ; Tomas, Davor ; Marković, Leon ; Varošanec, Ana Maria ; Bačić, Mateja ; Njirić, Niko
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni
Izvornik
Wnt Meeting 2016 EMBO Conference
/ - , 2016
Skup
Wnt Meeting 2016 EMBO Conference
Mjesto i datum
Brno, Češka Republika, 14.09.2016. - 17.09.2016
Vrsta sudjelovanja
Poster
Vrsta recenzije
Međunarodna recenzija
Ključne riječi
Wnt signaling ; human astrocytomas
Sažetak
Molecular and genetic landscapes of human astrocytic brain tumors still need elucidation. In the present study key players of Wnt signaling, beta-catenin (CTNNB1), TCF1 and LEF1, adenomatous polyposis coli (APC), AXIN1, SFRP3 and dishevelleds 1, 2 and 3 (DVL1, DVL2, DVL3) were investigated in human astrocytic tumors. Genetic changes were tested by PCR/loss of heterozygosity (LOH), microsatellite instability (MSI) and heteroduplex methods. Protein expressions were investigated by immunohistochemistry.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Zagreb
