Naslov
Gama delta TCR+ intestinal intraepithelial lymphocytes (i-IEL) could mediate the resistance to Trichinella spiralis infection by accelerating the worm expulsion
(Gama delta TCR+ intestinal intraepithelial lymphocytes (i-IEL) could medioate the resistance to Trichinella spiralis infection by accelerating the worm expulsion)

Autori
Božić, Frane ; Forčić, Dubravko ; Mažuran, Renata ; Marinculić, Albert

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Periodicum biologorum / Branko Vitale - Zagreb : Hrvatsko prirodoslovno društvo, 1995

ISBN
0031-5362

Skup
Annual Meeting on Immunology

Mjesto i datum
Zagreb, Hrvatska, 23.11.1995. - 24.11.1995

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
intraepithelial lymphocytes; parasite

Sažetak
Resistance to T. spiralis infection is associated with accelerated expulsion of adult worms, decreased fecundity of female worms, and decreased muscle larval burdens. To assess the role of γ δ TCR T cells in the control of the timing of the mucosal response to enteric parasitic infections, we used C57BL mice, orally infected with 200 viable T. spiralis larvae. We speculate that γ δ TCR of i­IEL during early stage of infection recognize and eliminate damaged epithelial cells generated by parasite antigens, concomitantly accelerating the worm expulsion.

Izvorni jezik
Engleski

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