Pregled bibliografske jedinice broj: 839245
Lipid/alginate nanoparticles for dexamethasone nasal delivery
Lipid/alginate nanoparticles for dexamethasone nasal delivery // 11th Central European Symposium on Pharmaceutical Technology
Beograd, Srbija, 2016. (predavanje, nije recenziran, sažetak, ostalo)
CROSBI ID: 839245 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Lipid/alginate nanoparticles for dexamethasone nasal delivery
Autori
Plantić, Ivana ; Čunčić, Ivan ; Jurišić, Bisera, Juretić, Marina, Pepić, Ivan ; Filipović-Grčić, Jelena ; Lovrić, Jasmina ; Hafner, Anita
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo
Skup
11th Central European Symposium on Pharmaceutical Technology
Mjesto i datum
Beograd, Srbija, 11.09.2016. - 24.09.2016
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
alginate; biocompatibility; Lecithin S100; Dimethyldioctadecylammonum bromide
Sažetak
In this work, we present the development of dexamethasone-loaded lipid/alginate nanoparticles that could provide prolonged dexamethasone release and prolonged residence time at the nasal mucosa, ensuring its local effect upon the administration of a lower dose. Prolonged residence time can be expected due to alginate bioadhesive properties, but could further be improved by adjusting alginate concentration in the nanoparticle suspension to the range in which it could form hydrogel in contant with calcium ions present in the nasal mucosa.
Izvorni jezik
Engleski
Znanstvena područja
Farmacija
POVEZANOST RADA
Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb
