Naslov
Implementing salivary cortisol assessment in large-scale population research in naturalistic settings: Insights from Croatian late adolescence stress study (CLASS)

Autori
Šupe-Domić, Daniela ; Milas, Goran ; Drmić-Hofman, Irena ; Rumora, Lada ; Martinović Klarić, Irena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Skup
International Union of Anthropological and Ethnological Sciences (IUAES) 2016 Inter kongres

Mjesto i datum
Dubrovnik, Hrvatska, 04.05.2016. - 09.05.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
biomarkers ; salivary cortisol ; psychosocial stress ; collection protocol ; late adolescence

Sažetak
Salivary cortisol is widely used in acute and chronic stress research, but very little is known about the typical functioning of the hypothalamic-pituitary-adrenal (HPA) axis in healthy adolescents in naturalistic settings. Our first goal was to develop a collection protocol for late adolescents that was a balance between a large population sample (needed for generalizability and statistical power) and a limited number of collected samples (allowing minimal disruption of typical daily routines). Our second goal was to gain basic knowledge about naturalistic HPA axis activity and to examine the influence of various predictors associated with diurnal cortisol rhythms in late adolescence. The total analytical sample consisted of 903 upper secondary school seniors aged 18 to 21 years, from two major types of schools (gymnasium/vocational), in four largest cities in Croatia. Cortisol was sampled at home at three time points (at awakening, 30 to 45 minutes after awakening and at bedtime) over the course of one day. Gender and awakening-bedtime rhythm were two major determinants of the naturalistic salivary cortisol profile in the population of Croatian upper secondary school seniors. Several other minor factors appeared to be associated with salivary cortisol indexes in various sub-groups of students: diet quality, smoking habits, history of drug abuse, school behavior and sexual experience. Obtained results offer a portrait of the typical functioning of the HPA axis in response to psychosocial challenges experienced in everyday lives in healthy late adolescents and provide grounds for identifying vulnerable groups with “risky” patterns of salivary cortisol activity.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija

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