Naslov
Cancer of the ovary, fallopian tube and peritoneum: surgical management

Autori
Danolić, Damir ; Alvir, Ilija ; Mamić, Ivica ; Kostić, Lucija ; Tomica, Darko ; Puljiz, Marko ; Puljiz, Mario

Izvornik
Libri oncologici : Croatian journal of oncology (0300-8142) 43 (2015), 1-3; 41-49

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, stručni

Ključne riječi
Cancer of the ovary; fallopian tube and peritoneum; surgical staging; debulking surgery; residual tumor

Sažetak
Surgery is the cornerstone of effective management of the ovarian, tubal and peritoneal cancer. In 2014 the International Federation of Gynecology and Obstetrics (FIGO) published a new classification collectively covering cancer of ovary, fallopian tube and peritoneum as well as malignant ovarian germ cell tumours and malignant sex-cord stromal tumours. Comprehensive surgical staging according to the 2014 FIGO classification system plays an important role in management of apparently early stage of ovarian, tubal and peritoneal cancer. Primary debulking (cytoreductive) surgery followed by paclitaxel and platinum based combination chemotherapy is the cornerstone of the advanced-stage disease treatment. In cases of suboptimal primary cytoreduction, interval debulking surgery performed after two to four cycles of chemotherapy based on the clinical judgment of the gynaecologic oncologist is second attempt to achieve optimal cytoreduction. Secondary cytoreductive surgery can be considered in patients with platinum-sensitive locally recurrent ovarian cancer. The volume of residual tumor remaining after these surgical approaches is one of the most important independent prognostic factors for survival.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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