Naslov
Quest for prostate tumor biomarkers by proteomic analysis in healthy and tumor tissue

Autori
Butorac, Ana ; Dodig, Ivana ; Solak Mekić, Meliha ; Rako, Duje ; Cindrić, Mario ; Bedalov, Goran ; Bulimbašić, Stela ; Balenović, Antonija ; Šamija, Ivan ; Šamija, Mirko

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
7th Central European Oncology Congress, final program & abstract book / Šamija, Mirko - Zagreb : Hrvatsko onkološko društvo, 2011, 56-56

Skup
7th Central European Oncology Congress

Mjesto i datum
Opatija, Hrvatska, 12.06.2011. - 15.06.2011

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
prostate cancer; biomarkers; proteomics

Sažetak
Prostate cancer is a complex and heterogenic disease, and heterogeneity of the disease represents a major hurdle to improve long-term survival. Identification of diagnostic and prognostic biomarkers can accurately describe the complexity and heterogeneity ascribed to prostate cancer. Predictive biomarkers are required to guide current treatment protocols, as well as to guide the development and application of new targeted therapies. 2-D gel-based expression proteomics workflow was used to compare the tumor and healthy prostate tissue proteomes. Eight patients were chosen for study of tumor and healthy prostate tissue proteomes. Paired (tumor and healthy prostate tissue) were isolated from 4 radical prostatectomy specimens.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA