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Pregled bibliografske jedinice broj: 833503

Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer

Bojanić, Kristina; Kizivat, Tomislav; Kuna, Lucija; Wagner, Jasenka; Smolić, Robert; Bilić-Čurčić, Ines; Kralik, Kristina; Smolić, Martina, Tucak, Antun; Včev, Aleksandar
Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer // IUAES - World anthropologies and privatization of knwoledge: engaing anthropology in public
Dubrovnik, Hrvatska, 2016. str. xx-xx (poster, nije recenziran, sažetak, ostalo)

CROSBI ID: 833503 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer

Autori
Bojanić, Kristina ; Kizivat, Tomislav ; Kuna, Lucija ; Wagner, Jasenka ; Smolić, Robert ; Bilić-Čurčić, Ines ; Kralik, Kristina ; Smolić, Martina, Tucak, Antun ; Včev, Aleksandar

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
IUAES - World anthropologies and privatization of knwoledge: engaing anthropology in public / - , 2016, Xx-xx

Skup
IUAES - World anthropologies and privatization of knwoledge: engaing anthropology in public

Mjesto i datum
Dubrovnik, Hrvatska, 04.05.2016. - 09.05.2016

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
pharmacogenetics ; breast cancer ; aromatase inhibitor ; adverse drug reactions ; osteoporosis ; hepatotoxicty

Sažetak
Anastrozole is a selective competitive aromatase inhibitor (AI) widely used as adjuvant treatment for early stage breast cancer. Highly efficient estrogen depletion by AI benefits breast cancer (BC) patients by extending recurrence-free survival. However, AIs put patients at high risk of osteoporosis due to the central role of estrogen in maintaining normal bone metabolism. Although awareness of osteoporosis by health care professionals has increased in recent years, it remains underdiagnosed and undertreated. Findings of this study should raise awarness of the importance of BMD screening among BC patients treated with anastrazole and to tailor treatment and prevention strategies for Al users as a high - risk population for bone morbidity. The intensity of adverse effects plays an essential part in maintaining patient complience to anastrazole therapy. Functional genetic polymorphisms of enzymes involved in anastrazole metabolism could be correlated to altered aromatase activity, disease prognosis and severity of aromatase inhibitor adverse effects, however large genotyping studies are obligatory.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA

Ustanove:
Medicinski fakultet, Osijek

Profili:

Avatar Url Robert Smolić (autor)

Avatar Url Ines Bilić-Ćurčić (autor)

Avatar Url Lucija Kuna Roguljić (autor)

Avatar Url Tomislav Kizivat (autor)

Avatar Url Jasenka Wagner (autor)

Avatar Url Kristina Bojanić (autor)

Avatar Url Kristina Kralik (autor)

Avatar Url Aleksandar Včev (autor)

Avatar Url Martina Smolić (autor)

Citiraj ovu publikaciju:

Bojanić, Kristina; Kizivat, Tomislav; Kuna, Lucija; Wagner, Jasenka; Smolić, Robert; Bilić-Čurčić, Ines; Kralik, Kristina; Smolić, Martina, Tucak, Antun; Včev, Aleksandar
Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer // IUAES - World anthropologies and privatization of knwoledge: engaing anthropology in public
Dubrovnik, Hrvatska, 2016. str. xx-xx (poster, nije recenziran, sažetak, ostalo)
Bojanić, K., Kizivat, T., Kuna, L., Wagner, J., Smolić, R., Bilić-Čurčić, I., Kralik, K., Smolić, Martina, Tucak, Antun & Včev, A. (2016) Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer. U: IUAES - World anthropologies and privatization of knwoledge: engaing anthropology in public.
@article{article, author = {Bojani\'{c}, Kristina and Kizivat, Tomislav and Kuna, Lucija and Wagner, Jasenka and Smoli\'{c}, Robert and Bili\'{c}-\v{C}ur\v{c}i\'{c}, Ines and Kralik, Kristina and V\v{c}ev, Aleksandar}, year = {2016}, pages = {xx-xx}, keywords = {pharmacogenetics, breast cancer, aromatase inhibitor, adverse drug reactions, osteoporosis, hepatotoxicty}, title = {Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer}, keyword = {pharmacogenetics, breast cancer, aromatase inhibitor, adverse drug reactions, osteoporosis, hepatotoxicty}, publisherplace = {Dubrovnik, Hrvatska} }
@article{article, author = {Bojani\'{c}, Kristina and Kizivat, Tomislav and Kuna, Lucija and Wagner, Jasenka and Smoli\'{c}, Robert and Bili\'{c}-\v{C}ur\v{c}i\'{c}, Ines and Kralik, Kristina and V\v{c}ev, Aleksandar}, year = {2016}, pages = {xx-xx}, keywords = {pharmacogenetics, breast cancer, aromatase inhibitor, adverse drug reactions, osteoporosis, hepatotoxicty}, title = {Patients complience correlates to pharmacogenomics of drugs used in the treatment of early stage breast cancer}, keyword = {pharmacogenetics, breast cancer, aromatase inhibitor, adverse drug reactions, osteoporosis, hepatotoxicty}, publisherplace = {Dubrovnik, Hrvatska} }

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