Naslov
Current Management and Novel Therapeutic Strategies to Combat Chronic Delta Hepatitis

Autori
Roguljić, Hrvoje ; Šarčević, Sonja ; Smolić, Robert ; Lučić Raguž, Nikola ; Včev, Aleksandar ; Smolić, Martina

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Drug Discovery and Development - From Molecules to Medicine

Urednik/ci
Valisuta, O ; Olimat, S

Izdavač
IntechOpen

Grad
Rijeka

Godina
2015

Raspon stranica
183-200

ISBN
978-953-51-2128-2

Ključne riječi
D virus infection ; polymerase chain reaction ; B surface antigen ; liver transplantation ; pegylated interferon-alpha-2B ; natural history ; peginterferon ; United States ; RNA ; replication

Sažetak
HDV is an unusal, defective hepatotropic virus which causes severe acute hepatitis and most progressive chronic viral hepatitis. Despite the efforts in eradication of HDV, as its obligatory helper HBV, prevalence of HDV in developed countries remains stable and represents a relevant public health concern. Current conventional therapy of hepatitis delta is characterized with poor overall response, thus further investigations of novel treatment options are needed. Continuous research of virology and pathogenesis is necessary to provide fundamentals for development of novel approaches in treatment of HDV.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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