Pregled bibliografske jedinice broj: 83110
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells.
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells. // Biomedicine & Pharmacotherapy, 56 (2002), 9; 458-462 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 83110 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
The effect of opioid agonists of delta-class DSLET, mu-class DAMGO, kappa-class U-69593 and an opioid antagonist, naloxone, on MTT activity of NALM-1 leukemic cells.
Autori
Martin-Kleiner, Irena
Izvornik
Biomedicine & Pharmacotherapy (0753-3322) 56
(2002), 9;
458-462
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
opioid agonists; NALM-1 leukemic cells; MTT-test
Sažetak
The effects of synthetic agonists of delta-, mu-, kappa-opioid classes were studied on proliferation of NALM-1 leukemic cells, using MTT-test. delta-opioid DSLET and mu-opioid DAMGO mildly and transiently decreased MTT-activity of NALM-1 cells after 6 hours treatment.The kappa-opioid agonist U-69593 mildly suppressed proliferation of NALM-1 cells after 48 hours treatment. Naloxone, an opioid receptor antagonist, mildly and transiently diminished MTT-activity of NALM-1 cells after 6 hours treatment. DAMGO, DSLET, U-69593, and an opioid antagonist naloxone did not trigger DNA fragmentation.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
Uključenost u ostale bibliografske baze podataka::
- Index Medicus
