Naslov
Structural Investigations of Aromatic Hydrazones in Solid State and in Solution

Autori
Galić, Nives

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
16th CEEPUS Symposium and Summer School on Bioanalysis / - , 2016

Skup
16th CEEPUS Symposium and Summer School on Bioanalysis

Mjesto i datum
Varšava, Poljska, 06.07.2016. - 15.07.2016

Vrsta sudjelovanja
Plenarno

Vrsta recenzije
Nije recenziran

Ključne riječi
aroylhydrazones; MS; NMR; IR spectroscopy; UV-Vis spectrometry

Sažetak
Aroylhydrazones derived from nicotinic acid hydrazide and differently substituted benzaldehydes (Scheme 1) were prepared according to the published procedure [1]. Such compounds can be involved in keto-enol tautomeric interconversion. Different tautomeric forms have different spectral properties and can be distinguished according to their IR, UV-Vis and NMR spectra. Structural investigations of title compounds in solid state and in solution were performed using following spectroscopic techniques: NMR (1H, 13C NMR, solid state NMR), IR spectroscopy, mass spectrometry (MS), UV-Vis spectrometry and spectrofluorimetry. Structural isomers of aroylhydrazones were distinguished by tandem mass spectrometry. Compounds 3 and 4 (derived from 3- and 4-hydroxy salicylaldehyde) as well as 8 and 9 (derived from 3- and 5-chloro salicylaldehyde) were distinguished by MS/MS as result of "ortho effect" [2]. The changes in UV-Vis spectra in DMSO during time were observed for 11, as well as for starting aldehyde 2-hydroxy-5-nitrobenzaldehyde.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

POVEZANOST RADA