Naslov
Successful treatment of risperidone-induced sexual dysfunction with bromocriptine

Autori
Šagud, Marina ; Jakovljević, Miro ; Mihaljević-Peleš, Alma ; Hotujac, Ljubomir ; Pivac, Nela ; Muck-Šeler, Dorotea

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstracts of the XXIIIrd Collegium Internationale Neuro-psychophyrmacologicum (CINP) Congress ; u: The International Journal of Neuropsychopharmacology 5 (2002) (S1) / Lerer, Bernard - Port Chester (NY) : Cambridge University Press, 2002, S171-S171

Skup
Collegium Internationale Neuro-psychophyrmacologicum Congress (23 ; 2002)

Mjesto i datum
Montréal, Kanada, 23.06.2002. - 27.06.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
schizophrenia; risperidone; bromocriptine; sexual dysfunction

Sažetak
Risperidone is an atypical antipsychotic, proved to be safe and effective in the treatment of schizophrenia. However, it has been reported to cause sexual dysfunction in males. This adverse event is beleived to be induced by increased prolactin levels and consequently decreased testosterone levels. The aim of the report is to present three case reports of risperidone-induced sexual dysfunction that was successfully reversed with addition of bromocriptine. Three males with the diagnoses of schizophrenia, aged 21, 24 and 49 years, were treated with risperidone 4 mg/daily. After two months of risperidone treatment, they complained on erectile dysfunctions and decreased libido. Bromocriptine 2, 5 mg in the morning was added to the current risperidone regimen. The aforementioned adverse events dissapeared in the next two to four weeks in all three patients. No worsening of psychosis was observed. In male schizophrenic patients with risperidone-induced sexual dysfunctions, who are otherwise in a stable remission, bromocriptine addition to risperidone dosage regimen should be considered as an useful alternative to the cessation of risperidone.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti

POVEZANOST RADA