Naslov
Infekcije i kardijalna kirurgija - prevencija, nadzor i liječenje
(Infections and cardial surgery - prevention, supervision and treatment)

Autori
Škrlin, Jasenka ; Sutlić, Željko ; Biočina, B ; Nikić, N ; Barić, D

Izvornik
Acta medica Croatica (1330-0164) 54 (2000); 81-92

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, stručni

Ključne riječi
antibiotik ; kardijalna kirurgija ; infekcija ; izolat
(antibiotic ; cardiac surgery ; infection ; isolate)

Sažetak
Microbiologic specimens and isolates referred during the period from October 1996 till December 1999 from the Divisions of Cardiac Surgery (CS) and of Cardiac Anesthesia and Intensive Treatment (CA), Dubrava University Hospital, were retrospectively analyzed. Microbiological surveillance was compared with clinical data of all patients operated on (n = 932) and patients with clinical signs of infection (n = 65). Of the total number of patients, 604 isolates were obtained from surveillance cultures of 304 (32.6%) patients. Staphylococcus aureus was the most common pathogenic isolate in surveillance cultures (n = 191 ; 31.6%). Microbiological surveillance included 204 CA patients (800 isolates) and 249 CS patients (870 isolates) after the operation and intensive treatment (CS(post)). Bronchial aspirates predominated in the referred material (n = 352 ; 44%). Methicillin resistant Staphylococcus epidermidis (MRSE) was the most common cause in the overall material from both CA (n = 99 ; 12.4%) and CS(post) (n = 237 ; 27.2%) patients. In the total number of treated patients, infection was recorded in 7%, whereas 14 (1.5%) patients died from infection. The prevention of infection in cardiac surgery patients requires continuous microbiological surveillance (surveillance cultures, intraoperative material, postoperative monitoring of microbiological flora), and targeted and optimal antibiotic therapy following perioperative prophylaxis. Based on the years long follow- up of all isolates and their antibiotic sensitivity, standardized perioperative protection has been performed in both CS and CA divisions of our hospital. The justifiability and efficiency of the therapeutic regimen and perioperative protection were supported by our results which yielded no compatibility of the pre- and postoperatively obtained isolates, whereas the prevalence of infection and the high mortality rate were consistent with current literature reports.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA