Naslov
Analysis of similarity/dissimilarity of DNA sequences based on novel 2-D graphical representation

Autori
Randić, Milan ; Vračko, Marjan ; Lerš, Nella ; Plavšić, Dejan

Izvornik
Chemical Physics Letters (0009-2614) 371 (2003), 1-2; 202-207

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
DNA; 2-D graphical representation; numerical characterization; similarity analysis

Sažetak
The recently proposed 2-D graphical representation of DNA based on four horizontal lines involves an arbitrary assignment of the four types of bases to the lines. While each such assignment is legitimate, it is desirable to have a scheme free of such arbitrary choices among non-equivalent geometrical representations. We outline one such approach, which is based on the construction of a 12-component vector whose components are the leading eigenvalues of the L/L matrices associated with DNA. The examination of similarities/dissimilarities among the coding sequences of the first exon of b-globin gene of different species illustrates the utility of the approach.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Biologija

POVEZANOST RADA