Naslov
Synthesis and conformational analysis of the repeating units of bacterial spore peptidoglycan

Autori
Keglević, Dina ; Kojić-Prodić, Biserka ; Banić-Tomišić, Zrinka

Izvornik
Carbohydrate Research (0008-6215) 338(12) (2003); 1299-1308

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Bacterial spore cortex repeating unit; Peptidoglycan; N-Acetylglucosamine; Muramic acid 1’; 2-lactam; Synthesis; NMR; X-ray Structure Analysis; Molecular modelling; Conformational analysis

Sažetak
Deprotection of the fully blocked disacharide allyl O-(2-amino-4, 6-O-benzylidene-3-O-[(R)-1-carboxyethyl]-2-deoxy-β -D-glucopyranosyl-1’ , 2-lactam)-(1→ 4)-2-acetamido-3, 6-di-O-benzyl-2-deoxy-β -D-glucopyranoside by selective de-O-allylation and parallel removal of the benzylidene and O-benzyl groups is described. The resulting β -muramyl lactam-(1→ 4)-GlcNAc disaccharide is characterised as the per-O-acetylated derivative by 1H and 13C NMR spectroscopy and X-ray structure analysis. Conformational analysis about glycosidic bond of repeating units of bacterial spore cortex is based on experimental data and molecular modelling.

Izvorni jezik
Engleski

Znanstvena područja
Kemija

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