Pregled bibliografske jedinice broj: 81591
New and improved 'LEGO' BLOCK protocols for the direct synthesis of hydrophilic ribbon molecules with acid, ester or peptide functionality
New and improved 'LEGO' BLOCK protocols for the direct synthesis of hydrophilic ribbon molecules with acid, ester or peptide functionality // TETRAHEDRON LETTERS, 41 (2000), 23; 4671-4675 (međunarodna recenzija, članak, znanstveni)
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Naslov
New and improved 'LEGO' BLOCK protocols for the direct synthesis of hydrophilic ribbon molecules with acid, ester or peptide functionality
Autori
Warrener, Ronald, N. ; Butler, Douglas, N. ; Margetić, D. ; Pfeffer, Frederick, M. ; Russell, Richard, A.
Izvornik
TETRAHEDRON LETTERS (0040-4039) 41
(2000), 23;
4671-4675
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
bicyclic aliphatic compounds; polycyclic aliphatic compounds; cycloadditions; epoxides; molecular design; peptides
Sažetak
Hydrophilic ribbon molecules are produced directly from the reaction of cyclobutene epoxide BLOCKs with norbornene dipolarophiles or indirectly by chemical modification of substituents in preformed lipophilic ribbon molecules. The formation of di- and tetra-acid chloride epoxides holds the key to the formation of ester, acid and amide BLOCKs which are active in 1, 3-dipolar cycloadditions with norbornene dipolarophiles, thereby delivering a wide range of substituents into the ribbon molecules and opening up combinatorial opportunities at each step.
Izvorni jezik
Engleski
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
