Pregled bibliografske jedinice broj: 815850
Therapeutic implication of molecular profiling in patients with non – small cell lung cancer
Therapeutic implication of molecular profiling in patients with non – small cell lung cancer // Periodicum biologorum, 114 (2012), 539-548 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 815850 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Therapeutic implication of molecular profiling in patients with non – small cell lung cancer
Autori
Jakopović, Marko ; Smojver-Ježek, Silvana ; Chalfe, Nabil ; Redžepi, Gzim ; Janković, Mateja ; Čučević, Branka ; Mihelčić, Dina ; Stančić- Rokotov, Dinko ; Samaržija, Miroslav ;
Izvornik
Periodicum biologorum (0031-5362) 114
(2012);
539-548
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
molecular biomarkers; non-small cell lung cancer
Sažetak
Traditional, 'one size fits all' approach to chemotherapy has reached efficacy plateau. The development of molecular biomarkers is crucial for improving efficacy of therapy in patients with NSCLC.We review prognostic and predictive value of molecular biomarkers with special overview on biomarker-driven personalized therapy of NSCLC. Main focus is this review is on significance of EGFR mutations and ALK – EML4 alterations on due to availability of targeted drugs against these specific aberrations.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Zagreb
Profili:
Gzim Redžepi
(autor)
Mateja Janković Makek
(autor)
Marko Jakopović
(autor)
Branka Čučević
(autor)
Silvana Smojver-Ježek
(autor)
Dinko Stančić-Rokotov
(autor)
Miroslav Samaržija
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus