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Pregled bibliografske jedinice broj: 813230

Personalizing health care: feasibility and future implications

Godman, B; Finlayson, AE; Cheema, PK; Zebedin-Brandl, E; Gutiérrez-Ibarluzea, I; Jones, J; Malmström, RE; Asola, E; Baumgärtel, C; Bennie, M et al.
Personalizing health care: feasibility and future implications // BMC Medicine, 11 (2013), 1. doi:10.1186/1741-7015-11-179 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 813230 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Personalizing health care: feasibility and future implications

Autori
Godman, B ; Finlayson, AE ; Cheema, PK ; Zebedin-Brandl, E ; Gutiérrez-Ibarluzea, I ; Jones, J ; Malmström, RE ; Asola, E ; Baumgärtel, C ; Bennie, M ; Bishop, M ; Bucsics, A ; Campbell, S ; Diogene, E ; Ferrario, A ; Fürst, J ; Garuoliene, K ; Gomes, M ; Harris, K ; Haycox, A ; Herholz, H ; Hviding, ; , Jan, S ; Kalaba, M ; Kvalheim, C ; Laius, O ; Lööv, SA ; Malinowska, K ; Martin, A ; McCullaghL, Nilsson, F ; Paterson, K ; Schwabe, U ; Selke, G ; Sermet, C ; Simoens, S ; Tomek, D ; Vlahović-Palčevski, V ; Voncina, L ; Wladysiuk, M ; van Woerkom, M ; Wong-Rieger, D ; Ali, R ; Gustafsson, LL.

Izvornik
BMC Medicine (1741-7015) 11 (2013), 1;

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Biomarkers ; Drug development ; Genomics ; Genotyping ; Healthcare policy ; Pharmacogenetics precision medicine ; Personalized medicine ; Health authorities ; Rational use of medicines ; Reimbursement ; Targeted treatments

Sažetak
Considerable variety in how patients respond to treatments, driven by differences in their geno- and/ or phenotypes, calls for a more tailored approach. This is already happening, and will accelerate with developments in personalized medicine. However, its promise has not always translated into improvements in patient care due to the complexities involved. There are also concerns that advice for tests has been reversed, current tests can be costly, there is fragmentation of funding of care, and companies may seek high prices for new targeted drugs. There is a need to integrate current knowledge from a payer’s perspective to provide future guidance. Multiple findings including general considerations ; influence of pharmacogenomics on response and toxicity of drug therapies ; value of biomarker tests ; limitations and costs of tests ; and potentially high acquisition costs of new targeted therapies help to give guidance on potential ways forward for all stakeholder groups. Overall, personalized medicine has the potential to revolutionize care. However, current challenges and concerns need to be addressed to enhance its uptake and funding to benefit patients

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita



POVEZANOST RADA

Ustanove:
Medicinski fakultet, Rijeka

Profili:

Avatar Url Vera Vlahović-Palčevski (autor)

Avatar Url Luka Vončina (autor)

Avatar Url Željko Schwabe (autor)

Avatar Url Rudolf Tomek (autor)

Poveznice na cjeloviti tekst rada:

doi http

Citiraj ovu publikaciju:

Godman, B; Finlayson, AE; Cheema, PK; Zebedin-Brandl, E; Gutiérrez-Ibarluzea, I; Jones, J; Malmström, RE; Asola, E; Baumgärtel, C; Bennie, M et al.
Personalizing health care: feasibility and future implications // BMC Medicine, 11 (2013), 1. doi:10.1186/1741-7015-11-179 (međunarodna recenzija, članak, znanstveni)
Godman, B., Finlayson, A., Cheema, P., Zebedin-Brandl, E., Gutiérrez-Ibarluzea, I., Jones, J., Malmström, R., Asola, E., Baumgärtel, C. & Bennie, M. (2013) Personalizing health care: feasibility and future implications. BMC Medicine, 11 (1) doi:10.1186/1741-7015-11-179.
@article{article, author = {Godman, B and Finlayson, AE and Cheema, PK and Zebedin-Brandl, E and Guti\'{e}rrez-Ibarluzea, I and Jones, J and Malmstr\"{o}m, RE and Asola, E and Baumg\"{a}rtel, C and Bennie, M and Bishop, M and Bucsics, A and Campbell, S and Diogene, E and Ferrario, A and F\"{u}rst, J and Garuoliene, K and Gomes, M and Harris, K and Haycox, A and Herholz, H and Hviding, and Kalaba, M and Kvalheim, C and Laius, O and L\"{o}\"{o}v, SA and Malinowska, K and Martin, A and Paterson, K and Schwabe, U and Selke, G and Sermet, C and Simoens, S and Tomek, D and Vlahovi\'{c}-Pal\v{c}evski, V and Voncina, L and Wladysiuk, M and van Woerkom, M and Wong-Rieger, D and Ali, R and Gustafsson, LL.}, year = {2013}, pages = {179}, DOI = {10.1186/1741-7015-11-179}, keywords = {Biomarkers, Drug development, Genomics, Genotyping, Healthcare policy, Pharmacogenetics precision medicine, Personalized medicine, Health authorities, Rational use of medicines, Reimbursement, Targeted treatments}, journal = {BMC Medicine}, doi = {10.1186/1741-7015-11-179}, volume = {11}, number = {1}, issn = {1741-7015}, title = {Personalizing health care: feasibility and future implications}, keyword = {Biomarkers, Drug development, Genomics, Genotyping, Healthcare policy, Pharmacogenetics precision medicine, Personalized medicine, Health authorities, Rational use of medicines, Reimbursement, Targeted treatments} }
@article{article, author = {Godman, B and Finlayson, AE and Cheema, PK and Zebedin-Brandl, E and Guti\'{e}rrez-Ibarluzea, I and Jones, J and Malmstr\"{o}m, RE and Asola, E and Baumg\"{a}rtel, C and Bennie, M and Bishop, M and Bucsics, A and Campbell, S and Diogene, E and Ferrario, A and F\"{u}rst, J and Garuoliene, K and Gomes, M and Harris, K and Haycox, A and Herholz, H and Hviding, and Kalaba, M and Kvalheim, C and Laius, O and L\"{o}\"{o}v, SA and Malinowska, K and Martin, A and Paterson, K and Schwabe, U and Selke, G and Sermet, C and Simoens, S and Tomek, D and Vlahovi\'{c}-Pal\v{c}evski, V and Voncina, L and Wladysiuk, M and van Woerkom, M and Wong-Rieger, D and Ali, R and Gustafsson, LL.}, year = {2013}, pages = {179}, DOI = {10.1186/1741-7015-11-179}, keywords = {Biomarkers, Drug development, Genomics, Genotyping, Healthcare policy, Pharmacogenetics precision medicine, Personalized medicine, Health authorities, Rational use of medicines, Reimbursement, Targeted treatments}, journal = {BMC Medicine}, doi = {10.1186/1741-7015-11-179}, volume = {11}, number = {1}, issn = {1741-7015}, title = {Personalizing health care: feasibility and future implications}, keyword = {Biomarkers, Drug development, Genomics, Genotyping, Healthcare policy, Pharmacogenetics precision medicine, Personalized medicine, Health authorities, Rational use of medicines, Reimbursement, Targeted treatments} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE

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