Pregled bibliografske jedinice broj: 813091
Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder
Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder // American journal of medical genetics, 74 (1997), 5; 504-506 doi:10.1002/(SICI)1096-8628(19970919)74:53.0.CO ; 2-G (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 813091 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Association analysis of the 5-HT2C receptor and 5-HT transporter genes in bipolar disorder
Autori
Oruč, L. ; Verheyen, G. R. ; Furač, Ivana ; Jakovljević, Miro ; Ivezić, Slađana ; Raeymaekers, P. ; Brohoven, C.
Izvornik
American journal of medical genetics (0148-7299) 74
(1997), 5;
504-506
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
serotonin receptor 2c (5-HTR2c) ; serotonin transporter (5-HTT) genes ; BAP
(receptor 2c (5-HTR2c) ; serotonin transporter (5-HTT) genes ; BAP)
Sažetak
We selected 42 patients with bipolar disorder type I (BPI) and 40 healthy controls for genetic analysis of DNA polymorphisms in the serotonin receptor 2c (5-HTR2c) and serotonin transporter (5-HTT) genes. No significant associations were found in the total patient sample. However, when the individuals were divided according to gender, trends for association with both polymorphisms (P = 0.051 for 5-HTR2c and P = 0.049 for 5-HTT) in female patients were observed. These results suggest that variations in these genes may be responsible for a minor increase in susceptibility for bipolar disorder in women.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Ustanove:
Medicinski fakultet, Zagreb,
Klinika za psihijatriju Vrapče,
Klinički bolnički centar Zagreb
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE
