Naslov
Three new Lactobacillus plantarum strains in the probiotic toolbox against gut pathogen Salmonella enterica serotype Typhimurium

Autori
Potočnjak, Mia ; Pušić, Petra ; Frece Jadranka ; Abram, Maja ; Janković, Tamara ; Gobin, Ivana

Izvornik
Food technology and biotechnology (1330-9862) 55 (2017), 1; 48-54

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
probiotic bacteria ; antagonistic activity ; Salmonella ; mechanism of action

Sažetak
The benefits of probiotic bacteria are widely explored. However, the research is not over and we present three new Lactobacillus plantarum strains isolated from different dairy products - cow cheese, sheep cheese and whey. In order to determine the antibacterial activity of yet unexplored Lactobacillus plantarum strains – A, B and S1, against Salmonella enterica serotype Typhimurium in vitro competition and co-culture tests were done. Furthermore, adhesion of these strains to Caco-2 cells and their influence on the adhesion of Salmonella were tested. Results showed the potential probiotic activity of isolated strains. They survive in the presence of 1% bile salts ; possess acidification ability, as well as antibacterial activity - reducing the number of S. Typhimurium. All tested L. plantarum strains were able to adhere to Caco-2 cells and significantly impair the adhesion of S. Typhimurium. They exhibited significant probiotic potential and anti-Salmonella activity, further testing on in vivo models should follow.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti, Biotehnologija

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