Pregled bibliografske jedinice broj: 812207
Genetic manipulation of ribosome biogenesis in inflammation-driven liver cancer
Genetic manipulation of ribosome biogenesis in inflammation-driven liver cancer // 3rd INFLA-CARE Annual Meeting
Atena, Grčka, 2011. (predavanje, nije recenziran, neobjavljeni rad, znanstveni)
CROSBI ID: 812207 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Genetic manipulation of ribosome biogenesis in inflammation-driven liver cancer
Autori
Volarević, Siniša
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, znanstveni
Skup
3rd INFLA-CARE Annual Meeting
Mjesto i datum
Atena, Grčka, 10.10.2011. - 11.10.2011
Vrsta sudjelovanja
Predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
ribosome biogenesis; cancer; inflammation
Sažetak
The increased demand for proteins during processes that require growth, such as proliferation, differentiation, malignant transformation and tumor progression the cell must increase translational capacity by up-regulating ribosome biogenesis. To manipulate ribosome biogenesis in vivo, we analyzed impact of conditional inactivation of one RPS6 allele on the DEN/PB- induced HCC and the relative contribution of the impaired protein synthesis and p53 activation to this therapeutic effect.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
POVEZANOST RADA
Projekti:
062-1081347-0370 - Odgovor stanica sisavaca na pogrešku u sintezi ribozoma in vivo (Volarević, Siniša, MZOS ) ( CroRIS)
Ustanove:
Medicinski fakultet, Rijeka
Profili:
Siniša Volarević
(autor)
