Naslov
The Relationship Between Gastroesophageal Reflux and Chronic Unexplained Cough in Children

Autori
Pavić, Ivan ; Čepin-Bogović, Jasna ; Hojsak, Iva

Izvornik
Clinical pediatrics (0009-9228) 55 (2016), 7; 639-644

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
cough ; gastroesophageal reflux ; weakly acidic ; children ; impedance-pH monitoring

Sažetak
The aim of this study was to assess the association between chronic cough and acid or weakly acid gastroesophageal reflux (GER) determined by 24-hour multichannel intraluminal impedance-pH monitoring and to assess whether the association is age dependent. Overall 150 children (mean age 7.5 years ; range 0.3-18.0 years ; male/female 90/60) were enrolled. Median of 87.5% (0% to 100%) of all cough episodes were associated with reflux ; 9% (0% to 100%) with acidic and 60% (0% to 100%) with weakly acidic episodes. In 52 children (34.7%), all cough episodes were associated with GER (100% association). Children younger than 2 years had significantly higher number of cough episodes associated with total (P = .03) and weakly acidic GER (P = .01). Binary logistic regression confirmed that only increase in age decreases the risk for complete (100%) association between cough episode and GER. Cough is significantly associated with weakly acidic GER and children of younger age are at higher risk.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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