Naslov
Cosyntropin for treatment of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP)

Autori
Sepčić, Juraj ; Radolović, Lorena ; Weiner-Črnja, Mima ; Rudež, Josip

Izvornik
ACTA FACULTATIS MEDICAE FLUMINENSIS (0065-1206) 23 (1998), 2; 85-87

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pismo, stručni

Ključne riječi
CIDP; Cosyntropin; Therapy

Sažetak
CIDP is manifested by inflammatory myelin lesion primarily in the roots and proyimal segments of peripheral nerves. The cause is not known. Immunological studies suggest that it is, a least partially, a T-cell-mediated disorder. The disease is eighter chronic or intermittent with exacebations. CIDP is diagnosed by clinical, electrophysiological, and histopathological findings, as well as cerebrospinal fluid (CSF) analysis. Immunomodulating steroids, plasma-exchange, or intravenous immunoglobulins are considered to be effective treatments. The patient presented in this letter is a case of the hypertrophic variant od CIDP, combined with CNS demyelinization. The administration of cosyntropin during relapses has always resulted in excellent remissions. We conclude that cosyntropin his its place in the CIDP treatment. The results of its application correlate with those obtained with much more expensive medications and/or procedures.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

POVEZANOST RADA