Naslov
Correlation of the VEMP score, ambulation and upper extremity function in clinically isolated syndrome

Autori
Crnošija, Luka ; Krbot Skorić, Magdalena ; Gabelić, Tereza ; Adamec, Ivan ; Brinar, Vesna ; Habek, Mario

Izvornik
Journal of the neurological sciences (0022-510X) 359 (2015), 1/2; 197-201

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
9-Hole Peg Test; Clinically isolated syndrome Timed 25-Foot Walk; Paced Auditory Serial Addition Test; Vestibular evoked myogenic potentials

Sažetak
Objective was to investigate the correlation of the vestibular evoked myogenic potential (VEMP) score with Timed 25-Foot Walk (T25FW), 9-Hole Peg Test (9HPT), Paced Auditory Serial Addition Test (PASAT) and EDSS in patients with multiple sclerosis (MS). This prospective, cross sectional study included 52 patients with clinically isolated syndrome (CIS). Cervical VEMP (cVEMP) and ocular VEMP (oVEMP), analyzed in the form of the cVEMP, oVEMP and VEMP scores, T25FW, 9HPT, PASAT and Expanded Disability Status Scale (EDSS) were performed. The only predictor of walking impairment in this study was general disability as measured by the EDSS, after controlling for age, gender, PASAT and EDSS the effect of VEMP score was non-significant (p=0.419). 9HPT of the dominant hand did not correlate with the oVEMP score (rs=0.258, p=0.065), however after controlling for age, gender, PASAT and EDSS, the effect of the oVEMP score on 9HPT of the dominant hand was statistically significant (p=0.017). After controlling for age, gender and oVEMP score, the effect of the PASAT on 9HPT variable for the non- dominant hand was statistically significant (p=0.001). We found possible effects of brainstem dysfunction on walking impairment, however they were not seen after correction for EDSS and cognitive dysfunction. On the other hand, dominant hand function seems to be influenced by upper brainstem dysfunction measured with oVEMP, while cognitive dysfunction is related to non- dominant hand function.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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