Naslov
Laboratory performances when using reference value as a target value in external quality assessment scheme in biochemistry

Autori
Vlašić Tanasković, Jelena ; Maradin, Ivana ; Jurčić, Gordana ; Leniček Krleža, Jasna

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
Abstracts of the ..... ; u Clinical chemistry and laboratory medicine 53 (2015) (11) / - , 2015, EA233-eA233

Mjesto i datum
,

Vrsta sudjelovanja
Poster

Vrsta recenzije
Nije recenziran

Ključne riječi
external quality assessment; reference value; consensus overall mean; allowable limit of performance

Sažetak
Background: External quality assessment provides an essential tool for medical laboratories which enables participants to evaluate both assay performances and established quality standards. Croatian Centre for Quality Assessment in Croatia provides quality assessment for biochemistry assays through corresponding module in every round of the scheme. The performance of each laboratory is evaluated using previously established allowable limits of deviation from consensus mean of comparison. In the last three rounds of the quality assessment scheme certified referent values based on reference methods has been assigned for 17 analytes. Reference values give the opportunity to access trueness of laboratory measurements procedures, especially when multiple instruments, reagents and calibrators are used. We compared the deviation of consensus overall mean from reference value for each of those 17 analytes and calculated the percentage of laboratories that met the criteria of allowable limits when both reference value and consensus overall mean were set as a target value. Materials and methods: The data reported during three biochemistry rounds have been reviewed. The biases of consensus means were calculated using formula: ((consensus mean – target value)/target value)x100. The number of laboratories that met the allowable limits of performance criteria was calculated first by defining minimum and maximum values allowed (min/max =  target value –/+ (allowable limit of performance% x target value)/100, ) and then counting the number of laboratories that fulfilled the criteria. Results: Average biases of consensus means ranged from 0, 69% (Na) to 9, 15% (CK). The percentage of laboratories that met the allowable limits of performance ranged from 66, 3 – 100% when consensus overall mean was set as a target value, whereas the range is 51, 1-100% when using reference value as target value. Conclusions: Deviations from target values were higher when reference values were set as target value and the extent of deviation depends on the analytes and the value.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Javno zdravstvo i zdravstvena zaštita

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