Naslov
Metabolic changes in chronic obstructive pulmonary disease.

Autori
Čepelak, Ivana ; Žanić-Grubišić, T ; Dodig, Slavica ; Romić, D ; Ruljančić, N ; Popović-Grle, Sanja ; Malić, Ana.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
EUROMEDLAB Amsterdam 2007 : 17th IFCC-FESCC European congress of chemistry and laboratory medicine ; 6oth National congress of Netherland Society for Clinical Chemistry and Laboratory Medicine (NVKC), Amsterdam, The Netherlands, June, 3-7 2007. Clinical Chemistry and Laboratory Medicine 2007 ; 45 (special suppl.) / - , 2007, S413-S414

Skup
EUROMEDLAB Amsterdam 2007

Mjesto i datum
Amsterdam, Nizozemska, 03.06.2007. - 07.06.2007

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Metabolic diseases; Chronic obstructive pulmonary disease
(etabolic diseases; Chronic obstructive pulmonary disease)

Sažetak
Chronic obstructive pulmonary disease (COPD) is the most common chronic respiratrory disease with the progressive course. Development of complications is associated with oxidative stress and progression of systemic inflammation and metabolic distrubances. Altered muscle amino acid metabolism resulting in skeletal muscle dysfunction is one oft he prominent systemic effects in COPD. We investigated extent of change sin the activities of enzymes involved int he aminoacid metabolism - alanine aminotransferase (ALT), aspartate aminotransferase (AST), gamma gluthamyl transferase (GGT) ; enzyme involved in bone rearrangement – alkaline phosphatase (ALP) and lactate dehydrogenase (LDH), enzyme reflecting hypoxia, characteristic of COPD patients. In addition, effect of cigarette smoking on these enzyme activities was also assessed.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA