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Pregled bibliografske jedinice broj: 788638

Genome-wide patterns of selection in 230 ancient Eurasians

Mathieson, Iain; Lazaridis, Iosif; Rohland, Nadin; Mallick, Swapan; Patterson, Nick; Alpaslan Roodenberg, Songül; Harney, Eadaoin; Stewardson, Kristin; Fernandes, Daniel; Novak, Mario et al.
Genome-wide patterns of selection in 230 ancient Eurasians // Nature, 528 (2015), 499-503 doi:10.1038/nature16152 (međunarodna recenzija, članak, znanstveni)

CROSBI ID: 788638 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Genome-wide patterns of selection in 230 ancient Eurasians

Autori
Mathieson, Iain ; Lazaridis, Iosif ; Rohland, Nadin ; Mallick, Swapan ; Patterson, Nick ; Alpaslan Roodenberg, Songül ; Harney, Eadaoin ; Stewardson, Kristin ; Fernandes, Daniel ; Novak, Mario ; Sirak, Kendra ; Gamba, Cristina ; Jones, Eppie R. ; Llamas, Bastien ; Dryomov, Stanislav ; Pickrell, Joseph ; Arsuaga, Juan Luís ; Bermúdez de Castro, José María ; Carbonell, Eudald ; Gerritsen, Fokke ; Khokhlov, Aleksandr ; Kuznetsov, Pavel ; Lozano, Marina ; Meller, Harald ; Mochalov, Oleg ; Moiseyev, Vyacheslav ; Rojo Guerra, Manuel A. ; Roodenberg, Jacob ; Vergès, Josep Maria ; Krause, Johannes ; Cooper, Alan ; Alt, Kurt W. ; Brown, Dorcas ; Anthony, David ; Lalueza-Fox, Carles ; Haak, Wolfgang ; Pinhasi, Ron ; Reich, David

Izvornik
Nature (0028-0836) 528 (2015); 499-503

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
ancient DNA; prehistory; Eurasia; natural selection

Sažetak
Ancient DNA makes it possible to observe natural selection directly by analysing samples from populations before, during and after adaptation events. Here we report a genome-wide scan for selection using ancient DNA, capitalizing on the largest ancient DNA data set yet assembled: 230 West Eurasians who lived between 6500 and 300 bc, including 163 with newly reported data. The new samples include, to our knowledge, the first genome-wide ancient DNA from Anatolian Neolithic farmers, whose genetic material we obtained by extracting from petrous bones, and who we show were members of the population that was the source of Europe’s first farmers. We also report a transect of the steppe region in Samara between 5600 and 300 bc, which allows us to identify admixture into the steppe from at least two external sources. We detect selection at loci associated with diet, pigmentation and immunity, and two independent episodes of selection on height.

Izvorni jezik
Engleski

Znanstvena područja
Arheologija



POVEZANOST RADA

Ustanove:
Institut za antropologiju

Profili:

Avatar Url Mario Novak (autor)

Poveznice na cjeloviti tekst rada:

doi www.nature.com

Citiraj ovu publikaciju:

Mathieson, Iain; Lazaridis, Iosif; Rohland, Nadin; Mallick, Swapan; Patterson, Nick; Alpaslan Roodenberg, Songül; Harney, Eadaoin; Stewardson, Kristin; Fernandes, Daniel; Novak, Mario et al.
Genome-wide patterns of selection in 230 ancient Eurasians // Nature, 528 (2015), 499-503 doi:10.1038/nature16152 (međunarodna recenzija, članak, znanstveni)
Mathieson, I., Lazaridis, I., Rohland, N., Mallick, S., Patterson, N., Alpaslan Roodenberg, S., Harney, E., Stewardson, K., Fernandes, D. & Novak, M. (2015) Genome-wide patterns of selection in 230 ancient Eurasians. Nature, 528, 499-503 doi:10.1038/nature16152.
@article{article, author = {Mathieson, Iain and Lazaridis, Iosif and Rohland, Nadin and Mallick, Swapan and Patterson, Nick and Alpaslan Roodenberg, Song\"{u}l and Harney, Eadaoin and Stewardson, Kristin and Fernandes, Daniel and Novak, Mario and Sirak, Kendra and Gamba, Cristina and Jones, Eppie R. and Llamas, Bastien and Dryomov, Stanislav and Pickrell, Joseph and Arsuaga, Juan Lu\'{\i}s and Berm\'{u}dez de Castro, Jos\'{e} Mar\'{\i}a and Carbonell, Eudald and Gerritsen, Fokke and Khokhlov, Aleksandr and Kuznetsov, Pavel and Lozano, Marina and Meller, Harald and Mochalov, Oleg and Moiseyev, Vyacheslav and Rojo Guerra, Manuel A. and Roodenberg, Jacob and Verg\`{e}s, Josep Maria and Krause, Johannes and Cooper, Alan and Alt, Kurt W. and Brown, Dorcas and Anthony, David and Lalueza-Fox, Carles and Haak, Wolfgang and Pinhasi, Ron and Reich, David}, year = {2015}, pages = {499-503}, DOI = {10.1038/nature16152}, keywords = {ancient DNA, prehistory, Eurasia, natural selection}, journal = {Nature}, doi = {10.1038/nature16152}, volume = {528}, issn = {0028-0836}, title = {Genome-wide patterns of selection in 230 ancient Eurasians}, keyword = {ancient DNA, prehistory, Eurasia, natural selection} }
@article{article, author = {Mathieson, Iain and Lazaridis, Iosif and Rohland, Nadin and Mallick, Swapan and Patterson, Nick and Alpaslan Roodenberg, Song\"{u}l and Harney, Eadaoin and Stewardson, Kristin and Fernandes, Daniel and Novak, Mario and Sirak, Kendra and Gamba, Cristina and Jones, Eppie R. and Llamas, Bastien and Dryomov, Stanislav and Pickrell, Joseph and Arsuaga, Juan Lu\'{\i}s and Berm\'{u}dez de Castro, Jos\'{e} Mar\'{\i}a and Carbonell, Eudald and Gerritsen, Fokke and Khokhlov, Aleksandr and Kuznetsov, Pavel and Lozano, Marina and Meller, Harald and Mochalov, Oleg and Moiseyev, Vyacheslav and Rojo Guerra, Manuel A. and Roodenberg, Jacob and Verg\`{e}s, Josep Maria and Krause, Johannes and Cooper, Alan and Alt, Kurt W. and Brown, Dorcas and Anthony, David and Lalueza-Fox, Carles and Haak, Wolfgang and Pinhasi, Ron and Reich, David}, year = {2015}, pages = {499-503}, DOI = {10.1038/nature16152}, keywords = {ancient DNA, prehistory, Eurasia, natural selection}, journal = {Nature}, doi = {10.1038/nature16152}, volume = {528}, issn = {0028-0836}, title = {Genome-wide patterns of selection in 230 ancient Eurasians}, keyword = {ancient DNA, prehistory, Eurasia, natural selection} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • MEDLINE
  • Nature Index

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