Pregled bibliografske jedinice broj: 787389
Chemometric estimation of the retention behavior of selected estradiol derivatives
Chemometric estimation of the retention behavior of selected estradiol derivatives // Acta Periodica Technologica, 46 (2015), 219-227 doi:10.2298/APT1546219K (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 787389 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Chemometric estimation of the retention behavior of selected estradiol derivatives
Autori
Karadžić, Milica ; Lončar, Davor ; Jevrić, Lidija ; Podunavac-Kuzmanović, Sanja ; Kovačević, Strahinja ; Jokić, Stela
Izvornik
Acta Periodica Technologica (1450-7188) 46
(2015);
219-227
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
estradiol derivatives ; chromatography ; QSRR ; lipophilicity ; linear regression
Sažetak
Quantitative structure-retention relationship (QSRR) analysis has been performed in order to correlate the retention of selected estradiol derivatives with their calculated molecular lipophilicity. The lipophilicity descriptors were derived computationally and most important were selected. Linear regression (LR) Wad used for model establishing. Statistical quality of the generated models was determined by standard statistical and crossvalidation statistical parameters. Statistically significant and physically meaningful models were obtained. The prediction results are very well correlated with the experimentally observed data. Given predictive ability of the established models indicates that they could be used for predicting the chromatographic behavior of the similar molecules in normal-phase high- performance thin-layer chromatography.
Izvorni jezik
Engleski
Znanstvena područja
Biotehnologija, Prehrambena tehnologija
Citiraj ovu publikaciju:
Časopis indeksira:
- Scopus
Uključenost u ostale bibliografske baze podataka::
- CAB Abstracts
