Naslov
Enhancement of insecticide efficacy by adipokinetic hormones

Autori
Kodrík, Dalibor ; Plavšin, Ivana ; Velki, Mirna ; Stašková, Tereza

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, znanstveni

Knjiga
Insecticides: Occurrence, Global Threats and Ecological Impact

Urednik/ci
Montgomery, Jaime

Izdavač
Nova Science Publishers

Grad
New York (NY)

Godina
2015

Raspon stranica
77-92

ISBN
978-1-63483-475-9

Ključne riječi
neurohormones, adipokinetic hormones, insecticides, pest control

Sažetak
Several studies showed that insect endocrine system, especially anti-stress neuropeptides, could be used as a potential target for the pest control. The main role of those neuropeptides is to eliminate or at least to reduce the impact of various stressors on insect organism. This defense response is primarily operated by neurohormones from adipokinetic hormone (AKH) family that control mainly stress energy metabolism. Several neurotoxic insecticides with oxidative-stress activity were tested in several model insect species and their anti-stress response was monitored by suitable markers. The results revealed increased level of AKH in corpora cardiaca, the endocrine glands near the insect brain where the AKHs are synthesized, and in hemolymph after the insecticide treatment. Further, the insecticide treatment affected some basic markers of oxidative stress: it modulated total antioxidative capacity as well as the activity of superoxide dismutase, catalase and glutathione-S-transferase, the main enzymes degrading principal toxic reactive oxygen metabolites. However, these discrepancies in oxidative stress markers were eliminated/reduced by co-application of insecticides with AKH. In general, the results showed unequivocal involvement of AKH to anti- stress reaction against the insecticidal action. Interestingly, it has been found that the AKH defense reaction against insecticide treatment can also be counter-productive: the co-application of insecticides with AKH increased significantly the insect mortality compared to that induced by the insecticides alone. This enhanced effect probably resulted from the stimulatory role of AKH on general metabolism: the carbon dioxide production was increased significantly after the co-treatment by AKH with insecticides compared to insecticide treatment alone. This elevation of metabolism could intensify the action of insecticides by its faster penetration into tissues and by an accelerated rate of exchange of metabolites including toxic ones, and resulted to higher mortality. On the other hand, the changes in oxidative stress markers were probably not included in the mechanisms responsible for increased insect mortality.

Izvorni jezik
Engleski

Znanstvena područja
Biologija

POVEZANOST RADA