Naslov
Hair aluminum status in Croatia

Autori
Mimica, Ninoslav ; Prejac, Jura ; Višnjević, Vjeran ; Skalny Andrey A. ; Momčilović, Berislav

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Journal of Trace Elements in Medicine and Biology 32S - Abstracts XI ISTERH Conference / Jurasović, Jasna ; Aschner, Michael - Amsterdam : Elsevier, 2015, 43-43

Skup
ISTERH 2015 - Recent Advances in Trace Element Research in Health and Disease

Mjesto i datum
Srebreno, Hrvatska, 18.10.2015. - 22.10.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Aluminum; hair; status; Croatia

Sažetak
Aluminum (Al) is omnipresent non-essential trace element in the human diet and an essential component of numerous industrial products and processes. The population environmental Al exposure risk is increasing, but there is no available long term biomarker for the population exposure assessment. In this observational, cross- sectional, exploratory, prospective epidemiological study we have studied hair aluminum (Al) in 1073 (339 men, 734 women) apparently healthy adult subjects from the capital city region of Zagreb, Croatia. Hair samples were analyzed by ICP-MS. We used the logistic bioassay sigmoid curve of median derivatives to further analyze natural distribution of Al in the hair. Men accumulated more HA1 then women (median men=7.64 pg-g"1 vs. median women=6.18 pg-g"1). The physiologically tolerable range in the linear part of the sigmoid curve is D3 - U3 (2.39-27.74 pg-g"1) for men and d3 - u3 (1.83- 20.92 pgg"1) for vvomen. Hair Al concentrations below or above this range indicate low (threshold) Al exposure or the excessive environmental Al exposure, respectively. Here we presented a novel concept on how to assess the environmental Al exposure risk by analyzing its frequency distribution properties in the hair. For the first time we report the unequivocal difference in Al deposition in the hair between men and women.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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