Naslov
Modulation of Aspergillus flavus NRRL 3251 oxidative status by fullerenol C60(OH)24: the interplay of TBARS and aflatoxin production

Autori
Kovač, Tihomir ; Šarkanj, Bojan ; Klapec, Tomislav ; Crevar, Biljana ; Đorđević, Aleksandar ; Kovač, Marija ; Nevistić, Ante ; Strelec, Ivica

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
3rd DocDay - Book of Abstracts / University of Natural Resources and Life Sciences (BOKU) Research Group Analytical Ecogeochemistry (VIRIS) - Tulln : University of Natural Resources and Life Sciences (BOKU) Research Group Analytical Ecogeochemistry (VIRIS), 2015, 44-44

Skup
3rd DocDay, PhD Conference

Mjesto i datum
Tulln, Austrija, 13.10.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
Aspergillus flavus; fullerenole C60(OH)24; oxidative stress; aflatoxin; TBARS

Sažetak
Aflatoxins (AFTs) are highly carcinogenic secondary metabolites of fungi genus Aspergillus which are produced under the oxidative and/or drought stress conditions of environment [1]. Thiobarbituric acid-reactive substances (TBARS) [2] are produced if the oxidative/antioxidative balance of the fungus cell is perturbed by reaction of free fatty acids and reactive oxidative species (ROS) [3]. One of the possible environmentally stressors are fullerenes C60 and their hydroxylated derivate fullerenols C60(OH)24 which are part of widespread commercial products [4, 5]. Oxidative stress, a pre-requisite for AFTs production, could be modulated by fullerenol C60(OH)24 nanoparticles, as possible antioxidants. Fullerenol C60(OH)24 nanoparticles caused statistically significantly decrease of AFTs production (p=0, 001). There was statistically significantly correlation between TBARS production (r=0.3213, p=0.0085) and detected AFTs in YES medium. Thereby, there is significant effect of fullerenol C60(OH)24 nanoparticles on modulation of oxidative status of Aspergillus flavus NRRL 3251 after 168 hrs growth in YES microbiological medium.

Izvorni jezik
Engleski

Znanstvena područja
Biotehnologija, Prehrambena tehnologija

POVEZANOST RADA