Naslov
Paternal genetic landscape of Croatian Eastern Adriatic islands in a wider European context

Autori
Šarac, Jelena ; Šarić, Tena ; Havaš Auguštin, Dubravka ; Rootsi, Siiri ; Missoni, Saša ; Villems, Richard ; Rudan, Pavao

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
European Journal of Human Genetics / - : European Society of Human Genetics, 2015, 347-348

Skup
European Human Genetics Conference

Mjesto i datum
Glasgow, Ujedinjeno Kraljevstvo, 06.06.2015. - 09.06.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Croatia; Eastern Adriatic islands; Y chromosome

Sažetak
Croatian Eastern Adriatic islands represent well-characterized genetic isolates, concerning their ethnohistory, biological traits, disease prevalence, migration patterns and environmental and sociocultural characteristics. Such small communities can reflect large demographic processes that happened in human prehistory and history and give us insight into the ancient migratory paths and forming of the Croatian and Southeast European gene pool. The aim of this study was to evaluate the level of isolation of insular populations based on the observed haplogroup distribution and frequencies of 720 samples from 12 Croatian subpopulations and to define the main processes that have shaped present Y chromosome variation of Eastern Adriatic islands and Croatia in general. A high level of haplogroup and haplotype diversity has been detected in the overall sample and the observed haplogroup frequency distributions correspond to an average European population, suggesting a dynamic gene flow in this region throughout history. The PCA plots show that the position of different Croatian subpopulations mostly corresponds to their actual geographic location. Also, it is noticeable that most of them are stretched along an axis, depending of the portion of I2a2-M423 and R1a-M458/M558 sublineages in their sample. Although the studied insular populations show an expected (mostly Paleolithic) paternal genetic structure corresponding to their geographic location, genetic structure of some islands exhibits interesting results due to the significant effect of evolutionary forces and specific historic episodes (like Lastovo, Cres and Dugi otok).

Izvorni jezik
Engleski

POVEZANOST RADA