Pregled bibliografske jedinice broj: 770593
Talens and CRISPR/Cas9: Generation of genome engineered mouse models using editable nucleases: Practical experience.
Talens and CRISPR/Cas9: Generation of genome engineered mouse models using editable nucleases: Practical experience. // KI-MU Closing Meeting: Cooperation between Masaryk University and Karolinska Institutet, Stockholm in the field of biomedicine
Brno, Češka Republika, 2014. (pozvano predavanje, nije recenziran, neobjavljeni rad, ostalo)
CROSBI ID: 770593 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Talens and CRISPR/Cas9: Generation of genome engineered mouse models using editable nucleases: Practical experience.
Autori
Sabol, Maja
Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, neobjavljeni rad, ostalo
Skup
KI-MU Closing Meeting: Cooperation between Masaryk University and Karolinska Institutet, Stockholm in the field of biomedicine
Mjesto i datum
Brno, Češka Republika, 22.04.2014. - 24.04.2014
Vrsta sudjelovanja
Pozvano predavanje
Vrsta recenzije
Nije recenziran
Ključne riječi
TALEN; CRISPR; mouse model
Sažetak
Targeting strategies based on programmable nucleases are a rapid and efficient system for site-specific knock-in and knock-out of gene of interest. These nucleases include zinc-finger nucleases (ZFN), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeats (CRISPR)/Cas RNA-guided nucleases. Therefore, the programmable nucleases are a method of choice for creation of mouse models where precision and speed is required. This presentation gives several practical examples of mouse models generated at the Czech Centre for Phenogenomics.
Izvorni jezik
Engleski
Znanstvena područja
Temeljne medicinske znanosti
