Naslov
Inkapsulacija kurkumina ionotropnim geliranjem u pektinski matriks sa različitim surfaktantima
(Curcumin encapsulation by iontropic gelation in pectin matrix with differnt surfactants)

Autori
Barić, Tihana

Vrsta, podvrsta i kategorija rada
Ocjenski radovi, diplomski rad, diplomski

Fakultet
Prehrambeno-biotehnološki fakultet

Mjesto
Zagreb

Datum
17.07

Godina
2015

Stranica
62

Mentor
Komes, Draženka

Ključne riječi
kurkumin; inkapsulacija; pektin; surfaaktant; topljivost; antioksidativna aktivnost
(curcumin; encapsulation; pectin; surfactant; solubility; antioxidative activity)

Sažetak
Aim of thesis was to encapsulate curcumin in pectin microparticles by iontropic gelation method to improve its solubility, bioavailability and to preserve its antioxidative activity. Five types of microparticles were produced. The study showed that the best surfactant is Solutol HS 15 for improving solubility of curcumin in water. Encapsulation efficiency is high in the case of all microparticles produced. Curcumin is stable at different environmental conditions through four days. Curcumin release from matrix of pectin microparticles was controlled for 7 hours and only in the case of Solutol microparticles 100% of release was achieved. Percentige of DPPH inhibition is reduced after encapsulation. Beta-lactoglobulin protects curcumin against the effects of temperature. Transportation of curcumin through the cell monolayer is transcellular. Solutol HS 15 showed to be highly toxic for cells.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija

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