Naslov
VERIFICATION OF TRAMADOL ABUSE IN PATIENTS ON METHADONE SUBSTITUTION THERAPY

Autori
Horvat, Vesna ; Mandić, Sanja ; Mandić, Dario ; Bojanić, Ksenija ; Majetić-Cetina, Neda

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Toxicology Letters 2006 ; 164, Supplement, Abstracts of the EUROTOX 2006/6 CTDC Congress — 43rd Congress of the European Societies of Toxicology & 6th Congress of Toxicology in Developing Countries, Cavtat, Croatia, 20-24 September 2006 / - Amsterdam : Elsevier, 2006, S70-S70

Skup
EUROTOX 2006/6 CTDC Congress — 43rd Congress of the European Societies of Toxicology & 6th Congress of Toxicology in Developing Countries, Cavtat, Croatia, 20-24 September 2006

Mjesto i datum
Cavtat, Hrvatska, 20.09.2006. - 24.09.2006

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
tramadol; emit; tlc; gc-ms

Sažetak
Methadone is a synthetic opioid, often used in the treatment of narcotic addiction. The oral use of methadone can suppress withdrawal symptoms, but in contrast to heroin, does not give any euphoric effect. However, this sensation can be induced by combination with alcohol, benzodiazepines, tramadol, etc. Therefore, regular urine testing should be carried out. We analyzed urines of 25 patients on methadone therapy with 3 methods: enzyme multiplied immunoassay (EMIT), thin layer chromatography (TLC) and gas chromatography mass spectrometry (GC–MS). We assessed the efficacy of these methods in verification of tramadol abuse in patients on methadone substitution therapy.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti

POVEZANOST RADA