Naslov
DEPRESSION IN PATIENTS ON DIALYSIS

Autori
Uglešić, Boran ; Lasić, Davor ; Vujnović, Zoran.

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
ABSTRACT BOOK 55th International Neuropsychiatric Congress / Vida Demarin, MD, PhD - Pula : Society for neuropsychiatry, Zagreb, Croatia, 2015, 68-68

Skup
55th International Neuropsychiatric Congress

Mjesto i datum
Pula, Hrvatska, 27.05.2015. - 30.05.2015

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Depression; Dialysis

Sažetak
Depression is a common psychiatric problem in patients undergoing dialysis. Several studies have been performed to validate depression in haemodialysis patients. The objective of this study was to compare the incidence of depression in the patients on dialysis (on hemodialysis /HD/ and on continuous ambulatory peritoneal dialysis /CAPD/). Some inflamation parameters such as the levels of C-reactive protein (CRP) and interleukin-6 (IL-6) were assesed, due to numerous reports which connect depression with inflammatory status. 52 patients on HD and 36 on CAPD were enrolled in this study. Depressive symptoms were measured with the Beck Depression Inventory (BDI). The BDI is a 21-item self-report instrument, and the elevated symptoms of depression were defined as a BDI score ≥16. HD patients were treated with high-flux polysulphone biocompatible dialyzers and CAPD patients were treated with usual dwell time (4-6 hours during the day and 8–10 hours at night). Depression (BDI ≥ 16) was present in 28.4% of dialysis patients, 35% of patients on hemodialysis (HD) and 18.1% of patients on continous ambulatory peritoneal dialysis (CAPD). The BDI score was significantly lower in CAPD patients comparing to HD patients, as well as the levels of albumin, C-reactive protein (CRP) and interleukin-6 (IL-6). IL-6 serum levels were similar in patients with depression and patients without depression in the whole group, as in HD patients. In CAPD patients without depression IL-6 levels were significantly lower. The prevalence of depression was higher in HD comparing to CAPD patients. Although IL-6 level was higher in HD compared to CAPD patients, the relationship between depression and presence of inflammation parametars were observed in CAPD, but not in HD patients.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

POVEZANOST RADA