Pregled bibliografske jedinice broj: 756940
Characteristics and frequency of DEL phenotype detected by indirect antiglobulin test in Dalmatia county of Croatia
Characteristics and frequency of DEL phenotype detected by indirect antiglobulin test in Dalmatia county of Croatia // Transfusion and apheresis science, 50 (2014), 2; 210-213 doi:10.1016/j.transci.2014.01.019 (međunarodna recenzija, članak, znanstveni)
CROSBI ID: 756940 Za ispravke kontaktirajte CROSBI podršku putem web obrasca
Naslov
Characteristics and frequency of DEL phenotype detected by indirect antiglobulin test in Dalmatia county of Croatia
Autori
Dajak, Slavica ; Krstić, Jelena ; Körmöczi, Gunther ; Dogić, Vesna ; Burilović, Vedrana
Izvornik
Transfusion and apheresis science (1473-0502) 50
(2014), 2;
210-213
Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni
Ključne riječi
Genotyping RHD; Indirect antiglobulin test; Weak D variants
Sažetak
D variants, collectively called DEL, express trace amounts of D antigen which is considered to be serologically detectable only by adsorption-elution techniques. We detected six cases of DEL phenotype by indirect antiglobulin test, in Dalmatia County of Croatia by routine serological testing of D antigen of new blood donors. RH genotyping found that all six donors carry allele RHD(M295I), RH genotype CcDdee. D antigen densities of D variants were very low, between 26 and 44 D antigens per red blood cell. The frequency of D variants detected by IAT allele RHD(M295I) was 1:272 in D negative donors. Obviously, DEL phenotype is more common in some parts of European population than initially thought. In conclusion, our routine serological testing of D antigen can detect extremely weak D antigen, even RBCs with DEL phenotype and antigen density as low as 26 D antigens per RBC.
Izvorni jezik
Engleski
Znanstvena područja
Kliničke medicinske znanosti
POVEZANOST RADA
Ustanove:
Hrvatski zavod za transfuzijsku medicinu,
Kineziološki fakultet, Split
Profili:
Slavica Dajak
(autor)
Citiraj ovu publikaciju:
Časopis indeksira:
- Current Contents Connect (CCC)
- Web of Science Core Collection (WoSCC)
- Science Citation Index Expanded (SCI-EXP)
- SCI-EXP, SSCI i/ili A&HCI
- Scopus
- MEDLINE