Naslov
Protective effect of polyphenols from chokeberry juice and powder (Aronia melanocarpa) on oxidative stress and hypercholesterolemia in C57BL mice

Autori
Tolić, Mandica-Tamara ; Nikolić, Lana ; Đikić, Domagoj ; Panjkota Krbavčić, Ines ; Vahčić, Nada ; Landeka Jurčević, Irena

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Book of Abstracts of the Congress of the Croatian Society of Biochemistry and Molecular Biology "The Interplay of Biomolecules", HDBMB 2014 / Katalinić, M. ; Kovarik, Z. - Zagreb : Hrvatsko Društvo za Biotehnologiju, 2014, 136-136

ISBN
978-953-95551-5-1

Skup
The Congress of the Croatian Society of Biochemistry and Molecular Biology "The Interplay of Biomolecules", HDBMB 2014

Mjesto i datum
Zadar, Hrvatska, 24.09.2014. - 27.09.2014

Vrsta sudjelovanja
Poster

Vrsta recenzije
Domaća recenzija

Ključne riječi
chokeberry juice ; chokeberry powder ; oxidative stress ; hypercholesterolemia

Sažetak
The potential hypolipidemic effect of chokeberry juice and powder (Aronia melanocarpa) was studied in a mice model of dietary-induced hypercholesterolemia. Animals were organized in groups (N=7/group) according to diet. For four weeks they were fed in the following order:1. normal diet (ND, control) ; 2. ND+Chokeberry juice ; 3.ND+Quercetin ; 4.ND+Powder (Aronia melanocarpa) ; 5.Cholesterol rich diet (CH) ; 6.CH+Chokeberry juice ; 7. CH+Quercetin ; 8. CH+Powder (Aronia melanocarpa). Lipid profile, transaminases as aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were measured in serum in addition to the activity of the antioxidant enzymes catalase (CAT), glutathione (GSH), superoxide dismutase (SOD) and malondialdehyde in the liver after the treatment period. Hypercholesterolemia and hypertriglyceridemia were established as a consequence of the cholesterol-rich diets. Hypercholesterolemic diet significantly increased (P<0.05) TC, TAG and LDL in comparison with normal diet. Treatment with chokeberry juice, powder (Aronia melanocarpa) or quercetin in hypercholesterolemic group significantly decreased TC, TAG and LDL in comparison with the hypercholesterolemic group (P<0.05) while HDL statistically significant magnified (P<0.05). The activities of hepatic superoxide dismutase (SOD), glutathione (GSH) and catalase (CAT) were found particularly increased in groups with chokeberry juice and powder treatment. These effects might be attributed to the high natural presence of antioxidant polyphenols. The consumption of powder (Aronia melanocarpa) with a hypercholesterolemic diet improved the lipidemic profile, reduced lipid peroxidation and increases antioxidant enzymes, suggesting that powder (Aronia melanocarpa) might contribute to a reduction of cardiovascular risk.

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija

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