Naslov
Preventing post-endoscopic retrograde cholangiopancreatography pancreatitis : What can be done?

Autori
Hauser, Goran ; Milošević, Marko ; Štimac, Davor ; Zerem, Enver ; Jovanović, Predrag ; Blažević, Ivana

Izvornik
World journal of gastroenterology (1007-9327) 21 (2015), 4; 1069-1080

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
Endoscopic retrograde cholangiopancreatography; Post-endoscopic retrograde cholangiopancreatography pancreatitis; Sphincterotomy

Sažetak
Post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) is the most common complication of endoscopic retrograde cholangiopancreatography. The incidence of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis varies substantially and is reported around 1%-10%, although there are some reports with an incidence of around 30%. Usually, PEP is a mild or moderate pancreatitis, but in some instances it can be severe and fatal. Generally, it is defined as the onset of new pancreatic-type abdominal pain severe enough to require hospital admission or prolonged hospital stay with levels of serum amylase two to three times greater than normal, occurring 24 h after ERCP. Several methods have been adopted for preventing pancreatitis, such as pharmacological or endoscopic approaches. Regarding medical prevention, only non- steroidal anti-inflammatory drugs, namely diclofenac sodium and indomethacin, are recommended, but there are some other drugs which have some potential benefits in reducing the incidence of post-ERCP pancreatitis. Endoscopic preventive measures include cannulation (wire guided) and pancreatic stenting, while the adoption of the early pre- cut technique is still arguable. This review will attempt to present and discuss different ways of preventing post-ERCP pancreatitis.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti

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